For patients who are 50, a baseline EKG is often performed. Fecal occult blood tests can also be used to detect colorectal cancer. At age 50, men are supposed to undergo a prostate exam, along with a prostate specific antigen, which is a blood test that can detect prostate cancer. Women over the age of 40 should get annual mammograms to screen for breast cancer. They should perform monthly self breast exam. They should also get routine pap smears, as well as pelvic exams. For women, it is also a good idea to undergo a bone mass test to screen for osteoporosis. So even if you feel like you're firing on all cylinders, be sure to rule out any underlying health issues by getting your annual physical.